Wednesday, 25 September 2013

ISCC to present new data for Parkinson's

International Stem Cell Corporation, a biotechnology company based in California, just issued a press release announcing that its chief scientific officer, Dr. Ruslan Semechkin, will present the latest results from its Parkinson's stem cell program at the American Neurological Association's 2013 Annual Meeting October 13 - 15, 2013 in New Orleans, LA.

Conducted in collaboration with the Sanford Burnham Medical Research Institute, the presentation will include new data and results from ISCO's first primate study, including an outline of neural stem cells' unique mechanism of action, data on the fate of the cells and a detailed analysis of the primate's immune response to the implantation. The presentation will be at the following session:

Date: Monday, October 14, 2013
Time: 11:00 am to 7:00 pm
Title: The Use of Neural Stem Cells for the Treatment of Parkinson's Disease in a Non-Human Primate Model

ISCO's Parkinson's disease program uses human parthenogenetic neural stem cells (hPNSC), a novel therapeutic cellular product derived from the company's proprietary histocompatible human pluripotent stem cells. The hPNSC are self-renewing multipotent cells that are precursors for the major cells of the central nervous system. The ability of hPNSC to (1) differentiate into dopaminergic neurons and (2) express neurotrophic factors such as glial derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) to protect the nigrostriatal system, offers a new and revolutionary opportunity for the treatment of Parkinson's disease, especially in cases where current dopamine-replacement approaches fail to adequately control the symptoms.

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