Tuesday, 26 February 2013

UCLA commences Phase III stem cell trial for coronary artery disease

According to the Examiner, the University of California, Los Angeles (UCLA) will soon commence a Phase III stem cell trial for patients with coronary artery disease. Purpose of the study is to test the safety and efficacy of autologous, blood-derived stem cells in restoring blood circulation.

The study will be placebo controlled and a total of 222 volunteers is expected to enrol. Half of the patients will receive placebo treatment and the other half will receive an autologous stem cell transplant. During the trial, CD34+ stem cells will be isolated from the patient's blood. They will then be cultured and injected directly into the heart with the help of a catheter inserted into the groin artery. Hopefully, the injected stem cells will form new heart cells or signal the local cells to create new blood vessels.

The participants will be followed for 5 years. Please be aware that you must have tried, with no success, all other conventional treatments. Neither the patients nor the doctors will know who is receiving the real stem cell treatment and who is getting a placebo. For more information about the trial please call 10-794-4797.

The trial is part of a bigger, multicentre study which aims to enrol more than 400 patients with the same conditions. According to the findings of the previous phase studies, the treatment is both safe and can yield some chest pain relief.

Co-principal investigator, Dr. Ali Nsair, said

“We’re hoping to offer patients who have no other options a treatment that will alleviate their severe chest pain and improve their quality of life.”



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1 comment:

  1. Such kind of studies are really beneficial. Injecting stem cells into the heart for curing the CAD (Coronary Artery Disease) is a great idea.Coronary artery disease is the most common reason of heart attack that is caused due to blood restriction to the heart. The patients getting the trail service would be blessed.

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