Thursday, 10 January 2013

Neural stem cells may help with Amyotrophic Lateral Sclerosis

A new promising study on Amyotrophic Lateral Sclerosis ( Lou Gehrig's disease) was published today. The study showed on an animal model that it is possible to repair the degenerated nervous system of ALS patients using stem cells.

During the study, mice with ALS were injected with human neural stem cells. These cells were derived from induced pluripotent stem cells. The cells quickly migrated to the spinal cord, matured and multiplied. According to the study the treatment was highly successful, as it improved both motor function by 15 %, and extended the mean life expectancy by 20 days.

Stefania Corti, author of the study, said:

"Our study shows promise for testing stem cell transplantation in human clinical trials" 

Image of neurons
AMS is the result of motor neuron degeneration

Amyotrophic lateral sclerosis (also known as Lou Gehrig’s Disease), is a incapacitating disease that ultimately leads to death. After the onset of symptoms, the mean life expectancy is around 40  months, with only a 4 % of patients managing to survive for more than 10 years. Current treatments can only slow down the progression of the condition.

Video about the Amyotrophic Lateral Sclerosis condition

- The study and its findings will be featured at the American Academy of Neurology's 65th Annual Meeting in San Diego (March 16-23, 2013)

- Stefania Corti is MD, PhD, at the University of Milan in Italy.

- A few days ago, researchers also released the results of 11 neural stem cell studies on ALS 


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